Genome-Wide Association Study Identifies Eight Novel Loci Associated with Blood Pressure Responses to Interventions in Han Chinese Running title: He et al.; Novel loci for BP responses
نویسندگان
چکیده
Jiang He, MD, PhD*; Tanika N. Kelly, PhD*; Qi Zhao, MD, PhD*; Hongfan Li, MD, PhD*; Jianfeng Huang, MD; Laiyuan Wang, MD, PhD; Cashell E. Jaquish, PhD; Yun Ju Sung, PhD; Lawrence C. Shimmin, PhD; Fanghong Lu, MD; Jianjun Mu, MD, PhD; Dongsheng Hu, MD; Xu Ji, MD; Chong Shen, MD, PhD; Dongshuang Guo, MD; Jixiang Ma, MD, PhD; Renping Wang, MD; Jinjin Shen, MD; Shengxu Li, MD, PhD; Jing Chen, MD; Hao Mei, MD, PhD; Chung-Shiuan Chen, MS; Shufeng Chen, MD, PhD; Jichun Chen, MD; Jianxin Li, MD; Jie Cao, MD; Xiangfeng Lu, MD; Xigui Wu, MD; Treva K. Rice, PhD; C. Charles Gu, PhD; Karen Schwander, MS; L. Lee Hamm, MD; Depei Liu, MD, PhD; Dabeeru C. Rao, PhD*; James E. Hixson, PhD*; Dongfeng Gu, MD, PhD*
منابع مشابه
Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.
BACKGROUND Blood pressure (BP) responses to dietary sodium and potassium intervention and cold pressor test vary considerably among individuals. We aimed to identify novel genetic variants influencing individuals' BP responses to dietary intervention and cold pressor test. METHODS AND RESULTS We conducted a genome-wide association study of BP responses in 1881 Han Chinese and de novo genotype...
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Correspondence and offprint requests to: Gerjan Navis; E-mail: [email protected] *Comments on Newton-Cheh C, Larson MG, Vasan RS et al. Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure. Nat Genet 2009; 41: 348–353; and on Newton-Cheh C, Johnson T, Gateva V et al. Genome-wide association study identifies eight loci associated with blood...
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تاریخ انتشار 2013